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ea0090oc3.3 | Oral Communications 3: Pituitary and Neuroendocrinology 1 | ECE2023

[18F]FET PET-MRI; a novel and improved technique for detection of small functional pituitaryadenomas

Pruis Ilanah , Balvers Rutger , Harteveld Anita , Feelders Richard , Vernooij Meike , Smits Marion , Verburg Erik , van Zanten Sophie Veldhuijzen , Neggers Sebastian

Background: Small functional pituitary adenomas can cause severely disabling symptoms and early death, however, surgical planning is often complicated due to inconclusive diagnostic MRI in up to 40% of patients and therefore hamper cure rates. We here introduce a novel method for the detection of small functional pituitary adenoma by O-(2-[18F]-fluoroethyl)-L-tyrosine ([18F]FET) PET-MRI.Methods: Patients with Cushings disease (CD) or acromegaly wit...

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ea0099p176 | Late-Breaking | ECE2024

[18F]FET PET-MRI; A diagnostic tool to improve medical decision-making for small functioning pituitary adenomas in acromegaly patients

van der Groef Romy , Pruis Ilanah , Balvers Rutger , Celine Refardt Julie , Veldhuijzen van Zanten Sophie , Neggers Sebastian

Background: Patients with acromegaly without detectable pituitary adenoma on conventional MRI are often excluded from adenomectomy due to inherent challenges of precise surgical planning, significantly limiting both their therapeutic options and chances of curation. Previous research showed that O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) PET-MRI is an accurate diagnostic tool to detect small functional pituitary adenomas (1). The present study aims to investigate the diagnos...

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Endocrine Abstracts

[18F]FET PET-MRI; a novel and improved technique for detection of small functional pituitaryadenomas

[18F]FET PET-MRI; A diagnostic tool to improve medical decision-making for small functioning pituitary adenomas in acromegaly patients

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